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The tally of annual infections and deaths becomes even more dramatic when C. The infection is rarely resistant to antibiotics but can cause Infection (11) - Refrain (CD) diarrhea and is often diagnosed in people who are taking antibiotics. About 12, people died and more thanpeople were infected with this germ inthe report said.

The number of C. Still, the number of cases outside health-care facilities increased, Infection (11) - Refrain (CD). In addition to those germs now circulating in the United States, the report identified a watch list of three germs with the potential to spread in the U. The CDC also described progress Infection (11) - Refrain (CD) fighting superbugs, particularly with heightened awareness among hospitals and health Infection (11) - Refrain (CD).

Greg Frank, an infectious disease expert at the Biotechnology Innovation Organization, said the report is a "really good first step" to describe and identify the worldwide challenge of curbing drug-resistant infections.

He said medical records helped produce more accurate figures than the CDC's report, but he still thinks some cases likely will be missed. There were concerns about aspects of the design and reporting of all the studies. In all of the studies healthy people had extractions of impacted wisdom teeth done by oral surgeons.

Additionally, there was no evidence that antibiotics prevent fever, swelling or problems with restricted mouth opening in patients who have had wisdom teeth removed. There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection.

Undertaking research in these groups of people may not be possible or ethical. However, it is likely that in situations where patients are at a higher risk of infection that preventative antibiotics may be beneficial, because infections in this group are likely to be more frequent and more difficult to treat. Another concern, which cannot be assessed by clinical trials, is that widespread use of antibiotics by people who do not have an infection is likely to contribute to the development of bacterial resistance.

The conclusion of this review is that antibiotics given to healthy people to prevent infections, may cause more harm than benefit to both the individual patients and the population as a whole.

Although general dentists perform dental extractions because of severe dental Infection (11) - Refrain (CD) or periodontal infection, there were no trials identified which evaluated the role of antibiotic prophylaxis in this group of patients in this setting.

All of the trials included in this review included healthy patients undergoing extraction of impacted third molars, often performed by oral surgeons. There is evidence that prophylactic antibiotics reduce the risk of infection, dry socket and pain following third molar extraction and result in Infection (11) - Refrain (CD) increase in mild and transient adverse effects.

It is unclear whether the evidence in this review is generalisable to those with concomitant illnesses or immunodeficiency, or those undergoing the extraction of teeth due to severe caries or periodontitis. However, patients at a higher risk of infection are more likely to benefit from prophylactic antibiotics, because infections in this group are likely to be more frequent, associated with complications and be more difficult to treat.

Due to the increasing prevalence of bacteria which are resistant to treatment by currently available antibiotics, clinicians should consider carefully whether treating 12 healthy patients with antibiotics to prevent one infection is likely to do more harm than good. The most frequent indications for tooth extractions are dental caries and periodontal infections, and these extractions are generally done by general dental practitioners.

Antibiotics may be prescribed to patients undergoing extractions to prevent complications due to infection. To determine the effect of antibiotic prophylaxis on the development of infectious complications following tooth extractions.

There were no restrictions regarding language or date of publication. We included randomised double- blind placebo -controlled trials of antibiotic prophylaxis in patients undergoing tooth extraction s for any indication.

Two review authors independently assessed risk of bias for the included studies and extracted data.


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